Atomic Force Microscopes, AFM Force Spectroscopy / Measurement, Novascan UV Ozone Cleaners, AFM Bead probes, AFM Chemical Probes, AFM Spring Constant Calibration, Anti-Vibration Acoustic Isolation>
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atomic force microscope uv ozone cleaner afm probe tip acoustic isolator
atomic force microscope uv ozone cleaner afm probe tip acoustic isolator
atomic force microscope uv ozone cleaner afm probe tip acoustic isolator
atomic force microscope uv ozone cleaner afm probe tip acoustic isolator
Chemically Modified Surfaces for Atomic Force Microscopy

Novascan Technologies glass and mica surfaces with defined chemistries are designed for use in:

  • Atomic Force Microscopy (AFM)
  • Confocal Microscopy
  • TIRF (Total Internal Reflection Flourescence)
  • Protein Binding Studies
  • Chemical Binding Studies
  • NSOM/SNOM (Nearfield Scanning Optical Microscopy)

Modified surfaces are comprised primarily of either thiol-based or silane-based self assembled monolayers (SAMs). Thiol modified surfaces, available with CH3, COOH, OH and succinimde end groups, are attached via chemical apsorption to a freshly applied layer of gold. Alternatively, silane monolayers, including APTES, are tethered to oxide layers on the surface of either glass or mica substrates. Further modifications can yield a variety of surface chemistries including NH3, maleimide, biotin, streptavidin, neutravidin, antibodies, PEG linkers and a number of other molecules.

Standard mica surfaces are 1cm x 1cm although custom sizing is available. Glass surfaces are 12mm round pieces, however other sizes may also be available. Be sure to mention custom requirements when inquiring. As is always the case at Novascan, we welcome the opportunity to discuss custom modifications including custom particle attachment or chemical modifications.

Potential Applications
  • Inter-molecular Force Measurement
  • Chemical Sensing and Detection
  • Hydrophilic/Hydrophobic Interaction
  • Attractive/Repulsive Regimes
  • Adhesion Forces
  • Unbinding Forces
  • Surface Mapping

Diagram of AFM tip modified with silane

Diagram of AFM tip modified with Thiol

atomic force microscope uv ozone cleaner afm probe tip acoustic isolator
atomic force microscope uv ozone cleaner afm probe tip acoustic isolator
atomic force microscope uv ozone cleaner afm probe tip acoustic isolator
atomic force microscope uv ozone cleaner afm probe tip acoustic isolator
atomic force microscope uv ozone cleaner afm probe tip acoustic isolator
Surfaces with Defined Chemistry

Mica Surfaces

Glass Surfaces

atomic force microscope uv ozone cleaner afm probe tip acoustic isolator
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